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Although macrophages have a remarkable ability to tolerate iron overload [117], the antioxidant capacity of macrophages is insufficient to cope with iron overload in this setting

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A case-control study found significantly decreased risk of age-related cataracts (33% to 51%) in men and women in the highest quintile of dietary riboflavin intake (median of 1.6 to 2.2 mg/day) compared to those in the lowest quintile (median of 0.08 mg/day in both men and women) (33)