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Medicines made from this hormone, known as glucagon-like peptide-1 receptor agonists (GLP-1 RAs), were originally designed to help those with type 2 diabetes to manage their blood glucose levels 2

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While it is well-established that intestinal GLP-1 cells can exert influence through paracrine mechanisms, recent evidence suggests the possible existence of synaptic-like connections between GLP-1 cells and peripheral neurons, including those of the vagus nerve

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The troglitazone induces cytochrome P450, leading to hepatotoxic reactive metabolites