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Dulaglutide (Trulicity) is a once-weekly injection that reduces hunger and slows digestion, similar to other effective GLP-1 medications

Mk is 20 or 25mg a day (no real benefit it going any more)

Lancet 2021;397(10278):97184

Supernatants collected were kept at 20C, then insulin was measured using the protocol below, and BCA assay (Thermo Scientific, 23227) was performed to normalize insulin secretion to total protein content

RCTs with longer follow-up are needed to determine long term efficacy, safety and risk for weight gain after treatment discontinuation

Appetite suppression changes what people eat and when, and a gut adapting to a new signalling pattern often handles very fatty, very sugary, or very large meals poorly