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GLP-1 receptors sit in the hypothalamus, the brain's temperature control center, so receptor activation can shift heat production and dissipation

Circ J 2010

Injecting directly into muscle is usually more painful than injecting into the subcutaneous layer of fat below the skin

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Here's what we'll cover Key takeaways While Ozempic (semaglutide)is considered safe, some people may experience mild side effects

Although either hyperpigmentation or hypopigmentation can occur, particular skin diseases tend to resolve with pigmentary sequelae of a certain type