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It's an investigational drug currently in Phase 3 clinical trials

Contrave : Seizures: Bupropion, one of the ingredients in Contrave , lowers the seizure threshold, increasing the risk in those prone to seizures

This reduces the pleasure and reward associated with eating, particularly high-calorie, palatable foods

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Researchers observed: Reduced liver injury markers Lower cholesterol and triglyceride levels Suppression of liver genes associated with fat production The authors concluded: These results suggest that GLP-1 analogs may provide an effective treatment option for patients with MC4R-POMC pathway deficiencies. Alternative brain and peripheral mechanisms The findings indicate that GLP-1 therapies may bypass defective MC4R signalling entirely

Physicians, also, get another option for obesity care