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The study found that cilastatin was associated with a 74% lower risk of AKI in randomized controlled trials (3 studies, 245 patients), and a 46% lower risk in observational studies (4 studies, 6,321 patients)
Additionally, medical supervision ensures that weight loss occurs at a safe and sustainable rate, reducing the risk of muscle loss or nutritional deficiencies
doi: 10.1210/jc.2017-02006 [DOI] [PubMed] [Google Scholar] 71.Maselli DB, Camilleri M
This conversation should also address realistic expectations for weight loss or glycemic improvement, potential side effects, and the commitment required for ongoing monitoring and medication adherence
Furthermore, the administration of GLP-1 agonists has expanded beyond diabetes management, with their potential application in obesity treatment
Glucagon-like peptide 1 receptor agonist discontinuation and risks of major adverse cardiovascular events in adults with type 2 diabetes: target trial emulation
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