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The challenge with liraglutide was its strong affinity for albumin, which lead to diminished potency for the GLP-1R and shorter plasma half-life and the reason for its once daily injectable dose
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[Cut to Amy Lynn.] Amy Lynn, speaking: Patients who are starting them just need to be aware that they may have some GI side effects including nausea, vomiting, constipation or diarrhea
These events contributed to macrophage pyroptosis and the progression of arthritis (65)
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