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Some patients, particularly those with neurological involvement, may benefit from more frequent dosing (every 2 months rather than 3 months), but this should be medically supervised rather than self-adjusted
Shooting water directly onto the powder creates foam, wastes peptide that gets trapped in bubbles, and can damage the molecule through mechanical stress
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In line with these findings, a study group found phosphorylated SN deposits in proximal peripheral nerves of PD patients with small nerve fiber PN compared to atypical parkinsonism and healthy controls, with no significant differences between LDopa exposure or Vit B12 deficiency (Donadio et al
