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Although there are promising novel therapeutic approaches, further research is needed to better understand the disease mechanisms, develop therapies that target difficult to reach tissues and create adjuvant therapies that address secondary cellular processes caused by the enzyme deficiency

Aspiration happens when substances like food or liquid accidentally enter a persons airways and lungs, according to the Washington State Department of Social and Health Services

16 Factors like ROS and impaired antioxidant systems can accelerate the process by damaging melanocytes in the outer root sheath and bulb, disrupting the renewal and migration of MSCs

Medication adjustment: If gastrointestinal side effects are contributing to back discomfort, discuss with your healthcare provider about slowing the titration schedule or temporarily holding at a lower dose until adaptation occurs

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