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It is hard identify ground zero for berberine as a supposed weight control substance, but a reasonable guess is that someone seeing the Ozempic bandwagon accelerate as it rolled by had the idea of scavenging through the scientific literature to find some substance that could be passed off as a bargain-basement relative

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Since satiety and reduced appetite are key contributors to weight loss, managing these symptoms while maintaining the therapeutic efficacy of GLP-1RAs should be carefully balanced

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