A medication review should be conducted to identify drugs that might contribute to cramping (statins, diuretics)
NLRP3 has been extensively linked to epilepsy, where heightened expression and activation is found in animal and human epilepsies as reviewed by Mohseni-Moghaddam et al., 2021
Clones were assigned to the same cluster if the receptor amino acids within both the heavy and light chain shared greater than 80% similarity, as measured by Levenshtein Distance 56 , in the primary amino acid sequence as well as identical V genes, J genes and identical CDR3 lengths
References Raun K, Hansen BS, Johansen NL, et al
This is not a pharmacogenomic test and does not predict exact medication response
Older men may find that appetite suppression feels more pronounced than in younger patients, partly because baseline appetite regulation may already be altered with age