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The hallmark of NAFLD is hepatic steatosis, but the disease also encompasses non-alcoholic steatohepatitis (NASH) characterized by hepatic inflammation, hepatocyte damage, and fibrosis, highlighting the potentially progressive nature of the disease

TNF-, Tumor Necrosis Factor-alpha

some references extend to ~16 weeks, followed by a 24 week pause

doi: 10.1111/j.1473-2165.2009.00471.x

470 In this study, researchers randomized 529 patients with heart failure with a preserved ejection fraction and body mass index (weight in kilograms in the square of the height in meters) 30 to receive once-weekly injections of semaglutide (2.4 mg) or placebo for 52 weeks