Our patients at Centra Internal Medicine noticed modest weight reduction within the first four weeks of treatment
Dehydration decreases tissue plumpness and elasticity
Semaglutide works by mimicking a hormone in your body that regulates blood sugar levels and helps control appetite
14,15 Because of the results of these landmark clinical trials, evidence-based treatment guidelines now recommend the GLP-1/GIP agonists as an important second-line treatment for uncomplicated type 2 diabetics who fail to meet hemoglobin A1c targets on popular first-line agents such as metformin
New oral formulations (Wegovy pill, upcoming oral tirzepatide) are cheaper to manufacture than injectables
The trial currently has almost 10,000 patients enrolled and is expected to assess a composite MACE endpoint consisting of cardiovascular (CV) death, non-fatal myocardial infarction, or non-fatal stroke in patients with T2D as is expected to readout in July 2024 (NCT03574597)