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In murine models of SIRT5-deficient hepatocellular carcinoma, in which cholesterol levels are elevated due to the inability to convert cholesterol to bile acids, treatment with cholestyramine, a bile acid sequestrant and FDA-approved drug for hyperlipidemia, effectively inhibited the promotion of M2-type polarized TAMs (106, 110)

In a 2021 review of studies of BSO and rheumatoid arthritis, there were multiple benefits, including a lower disease activity score, improved bone resorption, reductions in markers of oxidative stress and inflammation, and significant immunomodulatory activity

Tandem mass spectrometry (MS/MS) analysis

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Right and left myocardial antioxidant responses during heart failure subsequent to myocardial infarction

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