Additionally, it shows a greater ability to inhibit tyrosinase activity (an enzyme that produces melanin and causes hyperpigmentation) than other antioxidants used in skin care, such as kojic acid 2
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Its essential to maintain a sterile environment, follow recommended dosages, and monitor your B12 levels and any potential side effects
It also protects existing collagen from oxidative degradation slowing the breakdown of the protein that keeps skin firm and elastic
Research has explored its potential to support tissue repair, gut barrier integrity, and nervous system signaling pathways
A first-in-human, randomized, double-blind, placebo-controlled phase I study in healthy volunteers (clinical trial ID: NCT05027568) demonstrated that oral IOA-289 was well tolerated with no clinically significant adverse events