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This preservation of mitochondrial integrity may be attributed to the suppression of excessive mitochondrial ssion by the upregulation of adipose triglyceride lipase Atgl, the rate-limiting enzyme of triglyceride hydrolysis

Others, including Veranova, Aenova, and Biosynth, expanded capacities, while Ofichem strengthened its footprint with the acquisition of Avivia BV

Integrating UGT inhibition data into the rule-of-two model significantly enhances the prediction accuracy for drug-induced liver injury (DILI) (119)

All data were imported into GraphPad Prism version 9.0.1 (GraphPad Software Inc., San Diego, CA)

The existence of this mechanism has potentially important implications