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It can also increase insulin resistance, making it harder to lose weight and easier to gain weight

[52] While elders are more sensitive to GH, and thus more susceptible to the side effects of replacement with rhGH, stimulating production and secretion of endogenous GH with Sermorelin offers the advantage of a more physiological approach to increasing GH pulsatility while reducing risk for side effects

With non-surgical approaches, it may take several weeks to months