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193 Thymic epithelial cells (TECs) constitute the main cell population involved in thymic aging

Phase I metabolism introduces or unmasks functional groups on the compound, while Phase II metabolism adds endogenous molecules to the compound to enhance its hydrophilicity

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This version includes both N-acetylation and C-terminal amidation, structural changes that enhance peptide stability and resistance to enzymatic breakdown

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It should be noted that in addition to the Na + -dependent and Na + -independent GSH transporters, MRP (multidrug resistance-associated proteins), CFTR (cystic fibrosis transmembrane conductance regulator), and organic-anion-transporting polypeptide (OATP), especially oatp1 in OATP family, can also transport GSH [38] in addition to GSH derivatives such as glutathione disulfide (GSSG), glutathione S -conjugates, glutathione and metal complex [38]