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GLP-1 receptors are expressed in bone tissue, and preclinical studies have explored their role in bone metabolism

Osmotic laxatives (polyethylene glycol, lactulose): Draw water into the colon to soften stools

"These findings support a potential new therapeutic tool to effectively improve HbA1c levels well below 7 percent in such a challenging population," Rosenstock said in a statement

It has been possible to map the incretin function in humans in some detail owing to the availability of receptor antagonists for both hormones, namely exendin 9-39 for the GLP-1 receptor and the amidated GIP fragment GIP 3-30 amide for the GIP receptor [2]

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More research is needed into the effects of individual nutrients, specific foods, and dietary patterns in humans