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Before using GLP-1, tell your healthcare provider if you have any other medical conditions, including if you: have or have had problems with your pancreas or kidneys have type 2 diabetes and a history of diabetic retinopathy have or have had depression, suicidal thoughts, or mental health issues are pregnant or plan to become pregnant

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These thresholds reflect clinical evidence linking excess weight to cardiovascular and metabolic disease

She said introduce changes slowly and pay attention to how you feel

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[16] This meta-analysis of 16 RCTs involving 7024 participants found that GLP-1 agonists effectively lowered body weight compared with placebo