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According to the FDA prescribing information for both Ozempic and Wegovy, nausea, vomiting, diarrhea, abdominal pain, and constipation occur in a significant proportion of patients, particularly during dose escalation
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CONTRAINDICATIONS According to the package insert, Wegovy is contraindicated in patients with the following: personal or family history of Medullary Thyroid Carcinoma patients with Multiple Endocrine Neoplasm type 2 patients with a prior serious hypersensitivity reaction to semaglutide or to any of the excipients in Wegovy
The individual researcher preparing their own doses is a different scenario, but the underlying risks the FDA identified remain relevant