Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions
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Preliminary data point toward beneficial effects of GIP agonism, as reported in findings from the SURPASS program that tirzepatide reduced UACR and slowed down eGFR declined in comparison with both placebo (53) and comparator drugs including insulin glargine (74, 75)
To minimize multicollinearity issues, preference was given to continuous variables
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