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These results indicate consistent pathway-level signals across analytical platforms

These adipocyte-derived FAs promote the expression of G0S2, the hormone fibroblast growth factor 21 (FGF21) (149) and genes involved in FAO (150), and regulate liver FAO and very low-density lipoprotein (VLDL) secretion (150)

However, a link between excretion of these compounds and actual stone formation hasnt been established

In addition, later-stage organoids (Day 45) exhibit notable mesenchymal differentiation, expanding the potential applications of iHLOs to studies of complex liver pathologies such as fibrosis

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It stimulates the production of other essential pregnancy hormones