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What is the dosing protocol and titration schedule

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The high OCTN2 expression is associated with poor overall patient survival and a siRNA-mediated OCTN2 silencing in GBM led to a loss of tumor cell viability (Fink et al., 2019)

Since an IV dose is administered directly into the systemic circulation, it is assumed to have 100% bioavailability, or F = 1 and provide the reference standard for comparisons