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Traumatic brain injury accelerates amyloid-beta deposition and impairs spatial learning in the triple-transgenic mouse model of Alzheimer's disease

Athira Pharma's fosgonimeton (ATH-1017), part of the same HGF/c-Met program, failed the primary endpoint of its Phase 2/3 LIFT-AD Alzheimer's trial in September 2024

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When repeated administration is expected to be relevant for the future therapeutic use of the compound, the study may subsequently progress to a Multiple Ascending Dose (MAD) phase