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If irritation or discomfort occurs, discontinue use immediately

Common side effects include gastrointestinal symptoms (nausea, vomiting, diarrhoea, constipation), particularly during dose escalation, and gallbladder problems such as gallstones

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Furthermore, OS is an important pathomechanism in CKD, CKD-complications and CKD-progression [93, 94]

Titrate the dosage of the new medication according to its FDA-approved dosing schedule in partnership with your healthcare provider

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