Remember, the key to seeing real progress is consistency in both your peptide use and your workouts
Weight loss effectiveness Average weight loss expectations: 0.5mg daily: 8-10% over 24 weeks 1.0mg daily: 10-12% over 24 weeks Starting weight ~220 lbs: Lose 22-26 lbs Better than most weight loss medications Similar to GLP-1 agonists Individual variation: Timeline for weight loss: Week 1-2: 2-4 lbs (water weight + appetite suppression ) Week 3-4: 1-2 lbs/week (fat loss beginning) Month 2-3: 1-1.5 lbs/week (steady loss) Month 4-6: 0.5-1 lb/week (slowing, approaching plateau) Month 6-9: 0-0.5 lb/week (maintenance/plateau) Total: 20-30 lbs typical over 6 months Body composition changes: Primarily fat loss (75-80% of loss) Some muscle loss (20-25%) - unavoidable in deficit Better muscle preservation than pure caloric restriction Waist circumference reduction significant Visceral fat preferentially lost See peptides before and after results and how long peptides take to work

Symptoms of severe vitamin B12 deficiency can include visual disturbances, severe joint pain, paresthesia (tingling in the hands and feet), memory problems, depression, anxiety, poor muscle function, ataxia (impaired balance and coordination), changes in reflexes and even infertility
PLoS ONE 10:e0126978
The body is making the antioxidant, but the machinery required to utilize it is broken
REDEFINE 2 (Type 2 Diabetes) In patients with T2D, CagriSema produced significant weight loss alongside glycemic improvements (HbA1c reduction), outperforming the individual components (Lingvay et al., 2025)