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Effects of liraglutide on liver fat and metabolic parameters in PCOS: A randomized placebo-controlled trial

Proteins can unfold and lose their biological activity when subjected to mechanical stress

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[78] found that Lira inhibited proprotein convertase subtilisin/kexin type 9 (PCSK9) expression in HepG2 cells and db/db mice through hepatocyte nuclear factor 1 (HNF1)-dependent mechanism, and may inhibit LDLR expression in db/db mice through PCSK9 independent pathway, and ultimately reduce liver cholesterol accumulation