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Experiments have shown that the specific inhibitor of PIEZO1 can significantly reduce iron overload, inhibit mitochondrial oxidative stress, and block the characteristic changes of ferroptosis induced by mechanical stress (Liu et al., 2025)

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Plasma TNF levels were analysed by using the TNF alpha Mouse ProQuantum Immunoassay Kit (Thermo Fisher Scientific, Waltham, MA, United States) according to the manufacturers instructions

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