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None of these studies should be interpreted as recommending IGF-1 LR3 for human use, treatment, or any clinical purpose

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The most consistent and pronounced effect is on triglyceride reduction, with decreases of 15-30% observed in clinical trials

It was found that higher prevalence of Akkermansia levels in the gut microbiota are inversely related to insulin sensitivity, fasting glucose, waist-to-hip ratio, body fat mass, and plasma triglycerides, corroborating previous evidence in mice of the effects of Akkermansia for regulating metabolism

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