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Bertella L, Mori I, Grugni G, Pignatti R, Ceriani F, Molinari E, et al

Table 1 shows an overview of the key clinical advantages and challenging aspects of small molecules, peptide therapeutics, and mAbs

This compensation does not influence the information presented

Therapeutic use of GLP-1 tends to normalize alpha and beta cell sensitivity to glucose leading to improved glycemic control and reduced diabetic toxicity 7

These drugs may have serious side effects, so you will need frequent blood tests and other monitoring when taking them

Inhibitors of the MDM2/p53 interaction, such as UBX0101 and RG7112 (RO5045337), and inhibition of the de-ubiquitinating ubiquitin-specific peptidase 7 (USP7) increase and stabilize p53 levels and have been investigated for their senolytic effects