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Many patients may need long-term treatment to maintain results because obesity is a chronic condition, Dr Kaddaha adds

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Human dose recommendations in non-peer-reviewed sources are extrapolated from animal data or empirical observations and lack pharmacokinetic or pharmacodynamic validation

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The protected amino acid derivatives used were Fmoc-Lys(Boc)-OH, Fmoc-D-Phe-OH, Boc-D-2Nal-OH, Boc-His(Trt)-OH and Boc-Aib-OH (Boc-Amino isobutyric acid)