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Structurally modified to contain 83 amino acids, IGF-1 LR3 has a significantly longer half-lifeapproximately 20 to 30 hourscompared to natural IGF-1, which typically lasts only 1215 minutes in circulation (Clemmons, Trends in Endocrinology & Metabolism )

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For GHK-Cu specifically, MS analysis can also confirm the presence of the copper-bound complex versus the uncoordinated tripeptide, providing critical verification that the research material is the metal-peptide complex described in the literature

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Proc Natl Acad Sci USA (2017) 114(29):E580514