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The standard semaglutide dosing protocol starts at 0.25mg weekly and titrates up to 2.4mg over approximately 16 to 20 weeks

The STEP clinical trial program showed that participants achieved 1015% body weight reduction over 68 weeks, accompanied by improvements in cardiometabolic risk factors

During clinical trials, it had an unexpected but beneficial side effect: significant weight loss

Except most people interpret this as adding one extra glass per day and calling it done

Glucagon-like peptide-1 receptor agonists associated gastrointestinal adverse events: a cross-sectional analysis of the National Institutes of Health all of us cohort

Some people on semaglutide lose more than some people on retatrutide