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Lancaster et al., 2018), the expression of TLRs has been demonstrated in a number of EE cells and activation of this receptor triggers secretion of a number of metabolically active hormones such as GLP-1 (Lebrun et al., 2017), 5-HT (Larraufie et al., 2017

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PMID: 25069013

The efficacy and safety appear to be equivalent between the two methods, even though the interpretation is limited by the small numbers and heterogeneity of selected trials

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Possible side effects depend on the peptide used, dose, frequency, and the individual patient