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A limitation of this study is our inability to assess plasma or brain glucocorticoid levels

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This behooves us to carefully consider generalizations of neurophysiological observations from one form of dystonia to another, and to not discount the idea that similar abnormalities (like an impaired CBI or exaggerated plastic response to PAS M1 ) might stem from different causes

While tirzepatide has yet to demonstrate direct cardiovascular risk outcomes in patients without type 2 diabetes, tirzepatide-treated groups did demonstrate reductions in cardiometabolic variables resulting in a significantly lower 10-year predicted ASCVD risk in patients with overweight or obesity without type 2 diabetes in post hoc analysis of the SURMOUNT-1 trial [49]