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LR3 IGF-1 is a potent analog of IGF-1 with an extended N-terminal region that reduces binding to IGF-binding proteins, resulting in enhanced biological activity

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The researchers concluded that skin and hair effects are infrequent in patients on GLP-1 agonists, but the frequency does vary depending on the drug

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This is a common source of confusion

One of the most notable investigations, the STEP 1 trial published in The New England Journal of Medicine, reported that participants receiving weekly GLP1-S alongside lifestyle interventions experienced an average 14.9% decrease in body weight across 68 weeks[7][8]