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The schistosomicidal activities of PZQ and of potassium antimonial tartrate, a drug used in the past for schistosomiasis and a TGR inhibitor, are reduced in immunosuppressed mice 65 , indicating a crucial role of the host immune system in the mechanism of action of schistosomicidal agents in vivo

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Piracetam as a therapeutic agent for doxorubicin-induced cognitive deficits by enhancing cholinergic functions and reducing neuronal inflammation, apoptosis, and oxidative stress in rats

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Moreover, their primary role is to reduce peroxides, protecting cells from oxidative damage and maintaining cellular integrity

doi: 10.1093/humupd/dmz034 15 TrinchantRGarca-VelascoJ