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Headaches and Injection Site Reactions Headaches and injection site reactions, including mild redness or irritation at the weekly injection site, were also documented in trial participants, though these were less commonly reported than gastrointestinal symptoms
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The article pairs that with a set of contraindications and cautions, treating pregnancy as an absolute contraindication and stating that semaglutide should be stopped two months before conception on the basis of animal teratogenicity data
The corresponding fast infusion and high peak levels more likely approach the 5mg/kg suggested threshold for serotonin syndrome to occur
However, we must note that the patient cohort used in this study included both patients with and without diabetes, hence the results will not be applicable to everyone
