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Absorption is limited to approximately 1.5 g per dose through the intrinsic factor pathway, though passive diffusion allows absorption of about 1% of higher doses

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[118] Methionine synthase [edit] Methionine synthase, coded by MTR gene, is a methyltransferase enzyme which uses the MeB 12 and reaction type 2 to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine, thereby generating tetrahydrofolate (THF) and methionine

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