On the supportive side, the foundational cell-culture work reported that the distinct E-domain of MGF inhibits terminal differentiation of myoblasts while increasing their proliferation a behavior opposite to that of mature IGF-1, and one that would fit the proposed role of expanding the precursor pool before differentiation
Ethics declarations ETHICS APPROVAL AND CONSENT TO PARTICIPATE All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards
The four degradation factors are heat fluctuation, light and UV exposure, repeated freeze-thaw cycles, and contamination from non-sterile technique
CLINICAL GEM: GLP-1 drugs do not cure obesity
The result: no evidence of causation
Pancreatic & Gallbladder Health: There is a potential risk for pancreatitis and cholelithiasis (gallstones)