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403 Using an exploratory "cognitive age" calculation, Magtein was associated with an estimated 7.5-year reduction in brain age relative to the placebo group

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Quantitative real-time PCR (qRT-PCR) was conducted using the ABI Viia 7 Real-Time PCR System (Applied Biosystems, USA) with ChamQ SYBR qPCR Master Mix (Vazyme, China)