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Theyre the readouts that decide insurance coverage and label breadth, starting with the trial in people with obesity and established cardiovascular disease, which finished in spring 2026 with results expected later this year

The disrupted microbiome interacts with host immunity through mechanisms such as impaired TLR signaling, persistent inflammasome activation, and excessive protease release, all of which degrade extracellular matrix and hinder re-epithelialization

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