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Phentermine, in particular, carries a well-documented side effect profile that includes: Cardiovascular effects : elevated heart rate, increased blood pressure, and palpitations Central nervous system effects : insomnia, anxiety, restlessness, and dizziness Gastrointestinal symptoms : dry mouth, nausea, and constipation Dependence and withdrawal : phentermine has stimulant properties and carries a risk of psychological dependence with prolonged use Phentermine and related sympathomimetic agents are contraindicated in people with uncontrolled hypertension, ischaemic heart disease, arrhythmias, hyperthyroidism, glaucoma, or a history of drug or alcohol misuse

Intracellular GSH is synthesized through two reactions as shown in Fig

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Here are some steps you can take: Speak to your GP or prescribing clinician before making any changes to your medication about the digestive symptoms

10.1016/j.freeradbiomed.2008.09.001 29 DendrouC