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Flanagan RJ, Mant TG
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Since then, some other members of Ras family were described as the upstream regulators of PLC including Rap2 and TC21, which activate PLC in RA2-dependent manner in response to cell stimulation with EGF and activation of EGFR tyrosine kinase [11]
Similarly, redox potential was significantly reduced in APAP-treated animals (-206.77 0.65 mV for vehicle control vs -184.52 3.34 mv for APAP treated) consistent with increased oxidant exposure
Concomitant deficiencies (iron, folate), chronic illness, or drug interactions may blunt clinical response and warrant further evaluation
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