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Therefore, reducing the production of MMPs, inhibiting the activation of MMPs or increasing the production of endogenous inhibitors of MMPs are feasible strategies for the treatment of RA

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This tells us that slow initial response does not predict failure, a particularly relevant finding for microdosers who may not see dramatic changes in their early weeks at sub-therapeutic doses

[DOI] [PubMed] [Google Scholar] 16.Knudtson ML, Wyse KG, Galbraith PD