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The Mitochondrial Theory of Aging states that cellular function and energy loss comes from free radical damage to the cells

Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1.8 million participants

Conversely, on January 11, 2024, the Food and Drug Administration did not rule out a potential small risk and is conducting a meta-analysis of clinical trials and post-marketing data in the Sentinel System [181]

PMID: 39630530

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