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Tregs transfer cAMP to effector T cells with subsequent inhibition of NFAT (Nuclear factor of activated T-cells) and IL-2 (Interleukin-2) transcription and with subsequent cellular apoptosis ( The pivotal action of Tregs in autoimmune diseases, such as T1D (Type 1 diabetes), is well established

C., Richards J

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The Results In this study, 3,346 people with obesity, meaning a BMI over 30, but without diabetes started GLP-1 therapy and were compared to 8,343 similar people not using GLP-1 drugs

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