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3.2 Clostridium in RA RA is a kind of AD that affects the whole body and predominantly the joints (113), which is the result of immune dysregulation, such as aberrant immune activation and impaired immune tolerance (114)

Demonstrates anti-inflammatory and cytoprotective properties in preclinical settings [6]

The evidence bases are comparable in quality and scale, with both lacking large-scale randomized therapeutic trials

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Lotti, Institute of Occupational Medicine, University of Padua, Padua, Italy (Chairman) Professor D.R