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Peer review Peer review information Nature Communications thanks the anonymous reviewers for their contribution to the peer review of this work

This change could theoretically alter its enzymatic resistance, potentially making it more or less stable, but this is pure hypothesis without data

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Traditionally, farmed animals would have got their B12 from water and eating food from the ground but with so many now confined in factory farms, animals themselves are given B12 supplements

Matrixyl has been evaluated in several double-blind, placebo-controlled studies showing reductions in wrinkle depth and improvements in skin texture